SCHEMBL502867

SCHEMBL502867

c1ccc(-c2cccc(-c3ccccn3)c2)nc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.62
LMNA P02545 3/20 0.62
CCR1 P32246 3/20 0.62
CCR5 P51681 3/20 0.62
CCR8 P51685 3/20 0.62
CYP1A2 P05177 1/20 0.62
POLB P06746 1/20 0.62
METAP1 P53582 1/20 0.62
BLM P54132 1/20 0.62
HIF1A Q16665 1/20 0.62
DOHH Q9BU89 1/20 0.62
P4HTM Q9NXG6 1/20 0.62
CYP2A6 P11509 1/20 0.59
TP53 P04637 3/20 0.58
ALOX15 P16050 2/20 0.58
HTT P42858 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
ALPL P05186 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29679578 1.00 KDM4E (0.62) KDM4ELMNACCR1CCR5CCR8
SCHEMBL21506994 0.98 KDM4E (0.59) KDM4ELMNACCR1CCR5CCR8
Hydrochloric Acid SCHEMBL6007318 0.98 KDM4E (0.59) KDM4ELMNACCR1CCR5CCR8
SCHEMBL30533680 0.98 KDM4E (0.59) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28645180 0.95 KDM4E (0.56) KDM4ELMNACCR1CCR5CCR8
SCHEMBL21173056 0.95 KDM4E (0.56) KDM4ELMNACCR1CCR5CCR8
SCHEMBL11910168 0.95 KDM4E (0.56) KDM4ELMNACCR1CCR5CCR8
SCHEMBL30088399 0.93 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL650000 0.93 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL13799178 0.93 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof THE UNIVERSITY OF HONG KONG (CN) 2024-12-10 US claimed
CN-114957341-B Spiropyran platinum complex, preparation thereof and application thereof in light-operated hand-light switch material 杭州师范大学 2024-06-25 CN claimed
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF THE UNIVERSITY OF HONG KONG (CN) 2023-06-01 US claimed
CN-114957341-A Spiropyran platinum complex, preparation thereof and application thereof in light-operated chiral switch material 杭州师范大学 2022-08-30 CN claimed
CN-114524852-A Preparation method of temperature solvent double-response chiral platinum complex organic sol-gel 海南师范大学 2022-05-24 CN claimed
CN-108948092-B Solvent and temperature driven visual phosphorescent molecular hinge based on metal organic complex and synthesis method and application thereof 中山大学 2020-10-09 CN claimed
US-10378046-B2 Method of targeting mismatched DNA using d8 square planar metal complexes THE UNIVERSITY OF HONG KONG (CN) 2019-08-13 US claimed
US-20160369354-A1 METHOD OF TARGETING MISMATCHED DNA USING d8 SQUARE PLANAR METAL COMPLEXES THE UNIVERSITY OF HONG KONG (CN) 2016-12-22 US claimed
US-20110262897-A1 IMAGING TECHNIQUES USING A TRIDENTATE LIGAND SCIENCE AND TECHNOLOGY FACILITIES COUNCIL (GB) 2011-10-27 US claimed
US-12402524-B2 Dendrimers containing luminescent platinum(II) compounds for organic light-emitting devices and their preparation THE UNIVERSITY OF HONG KONG (CN) 2025-08-26 US disclosed
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof THE UNIVERSITY OF HONG KONG (CN) 2024-12-10 US disclosed
US-12116378-B2 Transition metal luminescent complexes and methods of use THE UNIVERSITY OF HONG KONG (CN) 2024-10-15 US disclosed
CN-114957341-B Spiropyran platinum complex, preparation thereof and application thereof in light-operated hand-light switch material 杭州师范大学 2024-06-25 CN disclosed
US-20230322691-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2023-10-12 US disclosed
US-20060093854-A1 Organometallic complex, light-emitting solid, organic electroluminescent element and organic electroluminescent display FUJITSU LIMITED (JP) 2006-05-04 US disclosed
US-7029766-B2 Organic element for electroluminescent devices EASTMAN KODAK COMPANY (US) 2006-04-18 US disclosed
US-20060073360-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. (JP) 2006-04-06 US disclosed
EP-1577300-A1 PLATINUM COMPLEXES Takasago International Corporation (JP) 2005-09-21 EP disclosed
WO-2005056717-A1 ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES EASTMAN KODAK COMPANY (US) 2005-06-23 WO disclosed
US-20050123788-A1 Organic element for electroluminescent devices GLOBAL OLED TECHNOLOGY LLC 2005-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12402524-B2 Dendrimers containing luminescent platinum(II) compounds for organic light-emitting devices and their preparation PDCD1LG2, PDCD2L, LIG3 KDM4E 4664/4885LMNA 3252/4885CCR1 453/4885
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof AGL, GMNN, GAK KDM4E 2397/4885LMNA 1450/4885CCR1 3987/4885
US-12116378-B2 Transition metal luminescent complexes and methods of use OCIAD2, OCIAD1, OPRD1 KDM4E 4696/4885LMNA 2898/4885CCR1 3876/4885
US-20230322691-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CCNT1, CCNE2, SCO2 KDM4E 3380/4885LMNA 701/4885CCR1 530/4885
US-20110262897-A1 IMAGING TECHNIQUES USING A TRIDENTATE LIGAND TIMM13, MPI, PARL KDM4E 3922/4885LMNA 3978/4885CCR1 675/4885
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF AGL, GMNN, GAK KDM4E 2397/4885LMNA 1450/4885CCR1 3987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.