SCHEMBL730330

SCHEMBL730330

c1ccc(-c2ccc3ccccc3c2)nc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.63
SMN1; SMN2 Q16637 6/20 0.63
LMNA P02545 4/20 0.63
ALDH1A1 P00352 3/20 0.63
MAPT P10636 3/20 0.63
TP53 P04637 2/20 0.63
PKM P14618 2/20 0.63
NPSR1 Q6W5P4 2/20 0.63
TSHR P16473 1/20 0.63
KLF5 Q13887 1/20 0.63
HSD17B10 Q99714 1/20 0.63
CYP1A2 P05177 6/20 0.53
CCR1 P32246 3/20 0.52
CCR5 P51681 3/20 0.52
CCR8 P51685 3/20 0.52
POLB P06746 1/20 0.52
METAP1 P53582 1/20 0.52
BLM P54132 1/20 0.52
HIF1A Q16665 1/20 0.52
DOHH Q9BU89 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29445842 1.00 KDM4E (0.63) KDM4ESMN1; SMN2LMNAALDH1A1MAPT
Hydrochloric Acid SCHEMBL29062272 0.98 KDM4E (0.61) KDM4ESMN1; SMN2LMNAALDH1A1MAPT
SCHEMBL26260190 0.96 KDM4E (0.57) KDM4ESMN1; SMN2LMNAALDH1A1MAPT
SCHEMBL13327726 0.94 KDM4E (0.57) KDM4ESMN1; SMN2LMNAALDH1A1MAPT
SCHEMBL26260209 0.94 KDM4E (0.56) KDM4ESMN1; SMN2LMNAALDH1A1MAPT
Boric Acid SCHEMBL28374351 0.93 KDM4E (0.56) KDM4ESMN1; SMN2LMNAALDH1A1MAPT
SCHEMBL12210848 0.89 MAPT (0.57) KDM4ESMN1; SMN2LMNAALDH1A1MAPT
SCHEMBL12579268 0.89 MAPT (0.57) KDM4ESMN1; SMN2LMNAALDH1A1MAPT
SCHEMBL12210948 0.89 KDM4E (0.57) KDM4ESMN1; SMN2LMNAALDH1A1MAPT
SCHEMBL10051456 0.89 MAPT (0.57) KDM4ESMN1; SMN2LMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160354-A Method for efficiently synthesizing aryl silicon compound 南阳师范学院 2022-10-11 CN claimed
EP-0671454-B1 Process for removal of heteroatoms EXXON RESEARCH ENGINEERING CO (US) 2000-09-06 EP claimed
US-5611915-A Process for removal of heteroatoms under reducing conditions in supercritical water EXXON RESEARCH AND ENGINEERING COMPANY (US) 1997-03-18 US claimed
EP-0671454-A2 Process for removal of heteroatoms EXXON RESEARCH AND ENGINEERING COMPANY (US) 1995-09-13 EP claimed
CN-117843688-A Organometallic compound, organic light emitting diode having the same, and organic light emitting device 乐金显示有限公司 2024-04-09 CN disclosed
CN-117843689-A Organometallic compound, organic light emitting diode having the same, and organic light emitting device 乐金显示有限公司 2024-04-09 CN disclosed
CN-113745437-B Organic light emitting device 乐金显示有限公司 2024-04-02 CN disclosed
CN-113745420-B Organic light emitting device 乐金显示有限公司 2024-04-02 CN disclosed
CN-113745436-B Organic light emitting device 乐金显示有限公司 2024-04-02 CN disclosed
WO-2024061920-A1 METHOD FOR ASSESSING THE ACTIVITY OF NICOTINAMIDE N-METHYLTRANSFERASE FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO Y POLITÉCNICO DE LA FE DE LA COMUNIDAD VALENCIANA (ES) 2024-03-28 WO disclosed
EP-4339296-A1 METHOD FOR ASSESSING THE ACTIVITY OF NICOTINAMIDE N-METHYLTRANSFERASE Fundación para la Investigación Hospital Universitario y Politécnico La Fe de la Comunidad Valenciana (ES) 2024-03-20 EP disclosed
CN-117596913-A Organic light emitting diode and organic light emitting device having the same 乐金显示有限公司 2024-02-23 CN disclosed
EP-1516901-A1 PHOSPHORS AND PROCESS FOR PRODUCTION THEREOF, LUMINESCENT COMPOSITIONS, AND ORGANIC ELECTROLUMINESCENT DEVICES AND PROCESSES FOR PRODUCTION THEREOF JSR Corporation (JP) 2005-03-23 EP disclosed
EP-1484380-A1 POLYMERIC PHOSPHORS, PROCESS FOR PRODUCTION THEREOF, PHOSPHORESCENT COMPOSITIONS AND ARTICLES MADE BY USING THE SAME JSR Corporation (JP) 2004-12-08 EP disclosed
EP-1484381-A1 PHOSPHORS, PROCESS FOR PRODUCTION THEREOF, PHOSPHORESCENT COMPOSITIONS AND ARTICLES MADE BY USING THE SAME JSR Corporation (JP) 2004-12-08 EP disclosed
US-20040106006-A1 Phosphors, process for production thereof, phosphorescent compositions and articles made by using the same JSR CORPORATION (JP) 2004-06-03 US disclosed
US-20040091739-A1 Polymeric phosphorescent agent and production process thereof, and luminescent composition and applied products thereof JSR CORPORATION (JP) 2004-05-13 US disclosed
US-20030162950-A1 Coupling catalyst and process using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2003-08-28 US disclosed
US-20030040627-A1 Luminescent organometallic compound and light emitting device SANYO ELECTRIC CO., LTD. (JP) 2003-02-27 US disclosed
CN-1397559-A Luminous organic intermetallic compound and luminous element SANYO ELECTRIC CO (JP) 2003-02-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162950-A1 Coupling catalyst and process using the same NOD1, PYM1, C9 KDM4E 3633/4885SMN1; SMN2 990/4885LMNA 1888/4885
US-20030040627-A1 Luminescent organometallic compound and light emitting device IK, CRY1, LBR KDM4E 3641/4885SMN1; SMN2 4724/4885LMNA 3413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.