Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21296425 | 1.00 | PTPN1 (0.43) | PTPN1KIF11SLC13A5CYP1A2PTPN7 | |
| SCHEMBL7743354 | 0.80 | MEN1 (0.57) | PTPN1KIF11SLC13A5CYP1A2PTPN7 | |
| SCHEMBL27505141 | 0.75 | PTPN1 (0.44) | PTPN1KIF11CYP1A2MEN1KMT2A | |
| SCHEMBL29730901 | 0.73 | MAPT (0.46) | KIF11CYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL27581398 | 0.72 | PTPN1 (0.39) | PTPN1KIF11 | |
| SCHEMBL4755686 | 0.71 | CYP1A2 (0.51) | PTPN1KIF11CYP1A2PTPN7KMT2A | |
| SCHEMBL514964 | 0.71 | CYP1A2 (0.51) | PTPN1KIF11CYP1A2PTPN7KMT2A | |
| SCHEMBL5970098 | 0.71 | CYP1A2 (0.51) | PTPN1KIF11CYP1A2PTPN7KMT2A | |
| SCHEMBL10387901 | 0.70 | CNR1 (0.40) | PTPN1KIF11 | |
| SCHEMBL28762466 | 0.68 | PPARA (0.43) | PTPN1KIF11SLC13A5CYP1A2PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081893-A1 | INTRACELLULAR TARGETING OF OLIGONUCLEOTIDES | ENTRADA THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2021127650-A1 | COMPOSITIONS FOR DELIVERY OF ANTISENSE COMPOUNDS | ENTRADA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| EP-3755351-A1 | COMPOSITIONS AND METHODS FOR TREATING MITOCHONDRIAL NEUROGASTROINTESTINAL ENCEPHALOPATHY | Entrada Therapeutics, Inc. (US) | 2020-12-30 | — | — | EP | disclosed |
| WO-2019165183-A1 | COMPOSITIONS AND METHODS FOR TREATING MITOCHONDRIAL NEUROGASTROINTESTINAL ENCEPHALOPATHY | ENTRADA THERAPEUTICS, INC. (US) | 2019-08-29 | — | — | WO | disclosed |