Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305912 | 0.81 | CYP1A2 (0.70) | MEN1KMT2ACYP1A2KIF11CYP2D6 | |
| SCHEMBL2089243 | 0.81 | CYP1A2 (0.70) | MEN1KMT2ACYP1A2KIF11CYP2D6 | |
| SCHEMBL2089245 | 0.81 | CYP1A2 (0.70) | MEN1KMT2ACYP1A2KIF11CYP2D6 | |
| SCHEMBL21296425 | 0.80 | PTPN1 (0.43) | MEN1KMT2ACYP1A2KIF11PTPN1 | |
| SCHEMBL21296426 | 0.80 | PTPN1 (0.43) | MEN1KMT2ACYP1A2KIF11PTPN1 | |
| Hydrochloric Acid SCHEMBL1630962 | 0.79 | CYP1A2 (0.68) | MEN1KMT2ACYP1A2KIF11CYP2D6 | |
| Water SCHEMBL8329268 | 0.79 | CYP1A2 (0.68) | MEN1KMT2ACYP1A2KIF11CYP2D6 | |
| SCHEMBL27843752 | 0.79 | CYP1A2 (0.68) | MEN1KMT2ACYP1A2KIF11CYP2D6 | |
| SCHEMBL4755686 | 0.78 | CYP1A2 (0.51) | KMT2ACYP1A2KIF11PTPN1PPARA | |
| SCHEMBL514964 | 0.78 | CYP1A2 (0.51) | KMT2ACYP1A2KIF11PTPN1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822827-A4 | ANTAGONISTS OF LHRH | UNIV TEXAS (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-0822827-A1 | ANTAGONISTS OF LHRH | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033729-A1 | ANTAGONISTS OF LHRH | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-10-31 | — | — | WO | disclosed |