Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514964 | 1.00 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C19PTPN1KIF11 | |
| SCHEMBL5970098 | 1.00 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C19PTPN1KIF11 | |
| SCHEMBL17545257 | 0.85 | CYP1A2 (0.48) | CYP1A2CYP2D6CYP2C19PKMCYP3A4 | |
| SCHEMBL17681750 | 0.83 | KIF11 (0.42) | CYP1A2CYP2D6CYP2C19PTPN1KIF11 | |
| SCHEMBL9043333 | 0.82 | PPARA (0.54) | PKMPPARAMAPTPTPN7 | |
| SCHEMBL9719820 | 0.81 | PTPN1 (0.49) | CYP2D6PTPN1KIF11CASRCYP3A4 | |
| SCHEMBL4678770 | 0.81 | PTPN1 (0.49) | CYP2D6PTPN1KIF11CASRCYP3A4 | |
| SCHEMBL11884018 | 0.81 | KDM4E (0.51) | CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL21296669 | 0.80 | KCNN4 (0.42) | CYP1A2PTPN1KIF11CASRSLC6A2 | |
| SCHEMBL7861321 | 0.80 | PTPN1 (0.47) | CYP2D6PTPN1KIF11CASRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111182880-A | WNT compositions and processes performed from serum-free culture conditions | 安卡萨再生疗法公司 | 2020-05-19 | — | — | CN | disclosed |
| CN-110891588-A | Peptidomimetic macrocycles and uses thereof | 艾瑞朗医疗公司 | 2020-03-17 | — | — | CN | disclosed |
| WO-2008156701-A2 | HYDROXAMATE INHIBITORS OF INSULIN-DEGRADING ENZYME AND USES THEREOF | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2008-12-24 | — | — | WO | disclosed |
| US-5849695-A | Parathyroid hormone analogues useful for treatment of osteoporosis and disorders of calcium meatabolism in mammals | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0539491-A4 | — | — | 1994-03-23 | — | — | EP | disclosed |
| EP-0539491-A1 | PARATHYROID HORMONE ANALOGUES MODIFIED AT POSITIONS 3, 6 or 9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-05-05 | — | — | EP | disclosed |
| WO-1992000753-A1 | PARATHYROID HORMONE ANALOGUES MODIFIED AT POSITIONS 3, 6 or 9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-01-23 | — | — | WO | disclosed |