Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 7/20 | 1.00 |
| ▸ | BCR | P11274 | 7/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29771944 | 0.91 | ABL1 (0.84) | ABL1ABCB1BCRESR2NPC1 | |
| SCHEMBL26731305 | 0.91 | ABL1 (0.84) | ABL1ABCB1BCRESR2NPC1 | |
| SCHEMBL20060981 | 0.86 | ESR2 (0.86) | ABL1ABCB1BCRESR2NPC1 | |
| SCHEMBL20060980 | 0.86 | ESR2 (0.86) | ABL1ABCB1BCRESR2NPC1 | |
| SCHEMBL1341494 | 0.83 | ESR2 (1.00) | ABL1ABCB1BCRESR2NPC1 | |
| SCHEMBL2274524 | 0.83 | ABL1 (0.79) | ABL1ABCB1BCRESR2NPC1 | |
| SCHEMBL15599404 | 0.83 | ESR2 (1.00) | ABL1ABCB1BCRESR2NPC1 | |
| SCHEMBL28162733 | 0.81 | ESR2 (0.95) | ABL1ABCB1BCRESR2NPC1 | |
| Ethane SCHEMBL27670651 | 0.81 | ABL1 (0.76) | ABL1ABCB1BCRESR2NPC1 | |
| Water SCHEMBL27689515 | 0.81 | ABL1 (0.76) | ABL1ABCB1BCRESR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107830520-A | A kind of burning-point burner | 徐州工程学院 | 2018-03-23 | — | — | CN | claimed |
| US-11389456-B2 | Compounds and methods for treating oxalate-related diseases | OXALURX, INC. (US) | 2022-07-19 | — | — | US | disclosed |
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2020-12-17 | — | — | US | disclosed |
| WO-2019165159-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. (US) | 2019-08-29 | — | — | WO | disclosed |
| CN-108250174-A | Naphtho-pyrans compounds and preparation method thereof | 中国科学院兰州化学物理研究所苏州研究院 | 2018-07-06 | — | — | CN | disclosed |
| CN-107830520-A | A kind of burning-point burner | 徐州工程学院 | 2018-03-23 | — | — | CN | disclosed |
| CN-106999382-A | Hair deformation process agent | 花王株式会社 | 2017-08-01 | — | — | CN | disclosed |
| CN-106866018-A | A kind of air entrained concrete activity excitant and preparation method thereof | 徐州工程学院 | 2017-06-20 | — | — | CN | disclosed |
| CN-104334326-B | Use the joint product that the adhesive composition containing tannin and the Louis acid catalysis of multifunctional aldehyde manufactures | 佐治亚-太平洋化工品有限公司 | 2016-12-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, LOX | ABL1 3986/4885ABCB1 2152/4885BCR 4193/4885 |
| US-11389456-B2 | Compounds and methods for treating oxalate-related diseases | XDH, PNPO, LOX | ABL1 3986/4885ABCB1 2152/4885BCR 4193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.