Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13554698 | 0.78 | KDM4E (0.48) | TOP1TSHRMAPK1HSD17B10NPC1 | |
| SCHEMBL1704912 | 0.77 | KDM4E (0.50) | TOP1TSHRMAPK1HSD17B10TGFBR1 | |
| SCHEMBL3432187 | 0.75 | KDM4E (0.48) | TOP1TSHRMAPK1HSD17B10TGFBR1 | |
| SCHEMBL13554704 | 0.68 | KDM4E (0.59) | TSHRMAPK1HSD17B10NPC1LMNA | |
| SCHEMBL25380095 | 0.67 | KDM4E (0.45) | TOP1TSHRMAPK1HSD17B10TGFBR1 | |
| SCHEMBL3210621 | 0.66 | KDM4E (0.53) | TSHRMAPK1HSD17B10TGFBR1NPC1 | |
| SCHEMBL30271293 | 0.65 | KDM4E (0.50) | TSHRMAPK1HSD17B10TGFBR1NPC1 | |
| SCHEMBL10336899 | 0.65 | KDM4E (0.50) | TSHRMAPK1HSD17B10TGFBR1NPC1 | |
| SCHEMBL13554700 | 0.65 | MYC (0.50) | TSHRHSD17B10NPC1LMNARAB9A | |
| SCHEMBL13554699 | 0.64 | MAPT (0.50) | TSHRHSD17B10NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392395-B2 | Nitrogen-containing aromatic compounds and metal complexes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392395-B2 | Nitrogen-containing aromatic compounds and metal complexes | TYR, MT-CO2, SOD1 | TOP1 2348/4885TSHR 4546/4885MAPK1 2683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.