Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17862989 | 0.90 | SIRT2 (0.43) | PTGER4HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL17862993 | 0.88 | PDE10A (0.46) | PTGER4PDE10AHDAC1HDAC8HDAC6 | |
| SCHEMBL17863008 | 0.85 | HDAC1 (0.45) | PTGER4HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL17862947 | 0.83 | SIRT2 (0.41) | PTGER4HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL17862981 | 0.82 | ESR1 (0.44) | PTGER4HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL17863007 | 0.81 | HDAC1 (0.43) | PTGER4HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL17862945 | 0.81 | PDE10A (0.43) | PTGER4PDE10AHDAC1HDAC8HDAC6 | |
| SCHEMBL17862990 | 0.81 | ESR1 (0.49) | PTGER4HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL17863019 | 0.81 | ESR1 (0.44) | PTGER4HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL17862281 | 0.80 | SIRT2 (0.42) | PTGER4HDAC1HDAC8HDAC6SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10396288-B2 | Organic electroluminescent element and electronic device | IDEMITSU KOSAN CO., LTD. (JP) | 2019-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10396288-B2 | Organic electroluminescent element and electronic device | RER1, LEF1, ELP1 | PTGER4 2311/4885PDE10A 4361/4885HDAC1 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.