Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21297492 | 0.81 | ALDH1A1 (0.39) | DDB1CRBNALDH1A1 | |
| SCHEMBL21297493 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL21540871 | 0.77 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL21540889 | 0.76 | ELANE (0.41) | DDB1CRBNALDH1A1 | |
| SCHEMBL21297491 | 0.76 | ELANE (0.41) | DDB1CRBNALDH1A1 | |
| SCHEMBL21540870 | 0.74 | DDB1 (0.38) | DDB1CRBNALDH1A1 | |
| SCHEMBL3696556 | 0.73 | DDB1 (0.49) | DDB1CRBN | |
| SCHEMBL12621202 | 0.71 | ALDH1A1 (0.53) | DDB1CRBNALDH1A1 | |
| SCHEMBL20457129 | 0.71 | ALDH1A1 (0.53) | DDB1CRBNALDH1A1 | |
| SCHEMBL2125064 | 0.70 | DDB1 (0.54) | DDB1CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392338-B2 | Spirofuranone compounds, derivatives thereof and processes for their preparation | Yissum Research Development Company, of The Hebrew University of Jerusalem Ltd. (IL) | 2019-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392338-B2 | Spirofuranone compounds, derivatives thereof and processes for their preparation | PKD1, PKD2, DHPS | DDB1 2078/4885CRBN 3230/4885ALDH1A1 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.