SCHEMBL21297532

SCHEMBL21297532

BCCNC(=O)OCCN(CI)CCOC(=O)NCCB

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.38
CHRNB2 P17787 2/20 0.34
CHRNB4 P30926 2/20 0.34
CHRNA3 P32297 2/20 0.34
CHRNA4 P43681 2/20 0.34
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21297500 0.79 ACHE (0.35) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL19197233 0.72 ACHE (0.42) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL25477800 0.67 ACHE (0.58) ACHE
SCHEMBL5600638 0.67 ACHE (0.51) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL14984051 0.66 ACHE (0.66) ACHE
SCHEMBL5601808 0.64 ACHE (0.64) ACHE
SCHEMBL13779876 0.64 TSHR (0.44) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL21297502 0.63
Hydrochloric Acid SCHEMBL9773760 0.63 CHRNB2 (0.49) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL25477796 0.63 ACHE (0.49) ACHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10394144-B2 Electrophotographic photosensitive body and image forming apparatus Konica Minolta, Inc. (JP) 2019-08-27 US disclosed