SCHEMBL21297548

SCHEMBL21297548

Cc1nccc2c3ccccc3c3ccccc3c12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.56
CYP1A2 P05177 3/20 0.50
MAOA P21397 2/20 0.50
CYP3A4 P08684 2/20 0.50
MAPT P10636 2/20 0.50
APEX1 P27695 2/20 0.50
MAPK1 P28482 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
GABRP O00591 1/20 0.50
GABRD O14764 1/20 0.50
CYP2D6 P10635 1/20 0.50
GABRA1 P14867 1/20 0.50
TSHR P16473 1/20 0.50
GABRB1 P18505 1/20 0.50
GABRG2 P18507 1/20 0.50
NFKB1 P19838 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21297546 0.81 CYP2A6 (0.52) CYP2A6CYP1A2MAOACYP3A4MAPT
SCHEMBL17532766 0.80 GPR3 (0.57) CYP2A6CYP1A2MAOACYP3A4MAPT
SCHEMBL26873055 0.78 CYP2A6 (0.63) CYP2A6CYP1A2MAOACYP3A4MAPT
SCHEMBL17532761 0.77 GPR3 (0.53) CYP2A6CYP1A2MAOACYP3A4MAPT
SCHEMBL22490104 0.76 CYP2A6 (0.55) CYP2A6CYP1A2MAOACYP3A4MAPT
SCHEMBL14341059 0.74 CYP2A6 (0.70) CYP2A6CYP1A2MAOACYP3A4MAPT
SCHEMBL26873305 0.74 CYP2A6 (0.70) CYP2A6CYP1A2MAOACYP3A4MAPT
SCHEMBL14341057 0.74 CYP2A6 (0.70) CYP2A6CYP1A2MAOACYP3A4MAPT
SCHEMBL12266516 0.73 CYP2A6 (0.56) CYP2A6CYP1A2MAOACYP3A4MAPT
SCHEMBL17051654 0.73 CCR1 (0.42) CYP2A6CYP1A2MAOACYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134873-A1 COMPOSITION, LAYER INCLUDING THE COMPOSITION, LIGHT-EMITTING DEVICE INCLUDING THE COMPOSITION, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-04 US disclosed
US-10396286-B2 Regioregular pyridal[2,1,3]thiadiazole π-conjugated copolymers for organic semiconductors THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-08-27 US disclosed