SCHEMBL22490104

SCHEMBL22490104

Cc1cc2ccnc(C)c2c2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.55
CCR1 P32246 1/20 0.44
CCR8 P51685 1/20 0.44
CYP1A2 P05177 5/20 0.40
TYMS P04818 1/20 0.40
KDM4E B2RXH2 3/20 0.39
MAOA P21397 2/20 0.39
CYP3A4 P08684 2/20 0.39
MAPT P10636 2/20 0.39
APEX1 P27695 2/20 0.39
MAPK1 P28482 2/20 0.39
MEN1 O00255 1/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2D6 P10635 1/20 0.39
GABRA1 P14867 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
GABRB1 P18505 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22489848 0.80 CYP2A6 (0.48) CYP2A6CCR1CCR8CYP1A2TYMS
SCHEMBL14341057 0.77 CYP2A6 (0.70) CYP2A6CYP1A2TYMSKDM4EMAOA
SCHEMBL26873055 0.76 CYP2A6 (0.63) CYP2A6CCR1CCR8CYP1A2MAOA
SCHEMBL21297548 0.76 CYP2A6 (0.56) CYP2A6CCR1CCR8CYP1A2KDM4E
SCHEMBL18643640 0.75 CYP1A2 (0.52) CYP2A6CCR1CCR8CYP1A2TYMS
SCHEMBL17532758 0.73 CYP2A6 (0.53) CYP2A6CYP1A2KDM4EMAOACYP3A4
SCHEMBL26873057 0.73 CYP2A6 (0.53) CYP2A6CCR1CCR8CYP1A2KDM4E
SCHEMBL597431 0.72 CYP1A2 (0.50) CYP2A6CCR1CCR8CYP1A2TYMS
SCHEMBL21297546 0.72 CYP2A6 (0.52) CYP2A6CCR1CCR8CYP1A2KDM4E
SCHEMBL17532761 0.72 GPR3 (0.53) CYP2A6CYP1A2KDM4EMAOACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200308205-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308205-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CYBA, CYC1, CRY2 CYP2A6 79/4885CCR1 1635/4885CCR8 3385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.