SCHEMBL21299317

SCHEMBL21299317

COP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@@H]1OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@@H]1OP(=O)(O)O[C@H]1C[C@H](n2cc(C)c(=O)[nH]c2=O)O[C@@H]1CO

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.63
▸ TERT O14746 2/20 0.56
▸ F2 P00734 1/20 0.50
▸ TK1 P04183 2/20 0.49
▸ RNASEL Q05823 3/20 0.47
▸ POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25896349 0.94 DTYMK (0.64) DTYMKTERTF2TK1
SCHEMBL29306797 0.94 DTYMK (0.64) DTYMKTERTF2TK1
SCHEMBL21299324 0.93 DTYMK (0.60) DTYMKTERTF2TK1POLB
SCHEMBL17268344 0.93 DTYMK (0.74) DTYMKTERTF2TK1RNASEL
SCHEMBL8612856 0.93 DTYMK (0.74) DTYMKTERTF2TK1RNASEL
SCHEMBL8613042 0.93 DTYMK (0.74) DTYMKTERTF2TK1RNASEL
SCHEMBL19147022 0.92 DTYMK (0.62) DTYMKTERTF2RNASEL
SCHEMBL25912829 0.92 DTYMK (0.69) DTYMKF2RNASEL
SCHEMBL29306731 0.92 DTYMK (0.69) DTYMKF2RNASEL
SCHEMBL19147041 0.89 DTYMK (0.59) DTYMKTERTF2RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3169693-B1 CHIMERIC POLYNUCLEOTIDES MODERNATX INC (US) 2022-03-09 — — EP disclosed
EP-3169335-B1 CIRCULAR POLYNUCLEOTIDES MODERNA THERAPEUTICS INC (US) 2019-08-28 — — EP disclosed
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