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SCHEMBL21299324

SCHEMBL21299324

COP(=O)(S)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@@H]1OP(=O)(O)O[C@H]1C[C@H](n2cc(C)c(=O)[nH]c2=O)O[C@@H]1CO

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.60
▸ TERT O14746 2/20 0.52
▸ F2 P00734 1/20 0.49
▸ TK1 P04183 3/20 0.48
▸ POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24325350 0.94 DTYMK (0.58) DTYMKTERTF2
SCHEMBL21299317 0.93 DTYMK (0.63) DTYMKTERTF2TK1POLB
SCHEMBL29306797 0.93 DTYMK (0.64) DTYMKTERTF2TK1
SCHEMBL25896349 0.93 DTYMK (0.64) DTYMKTERTF2TK1
SCHEMBL27062466 0.92 DTYMK (0.60) DTYMKTERTF2TK1POLB
SCHEMBL19147053 0.92 DTYMK (0.58) DTYMKTERTF2
SCHEMBL19069603 0.91 DTYMK (0.68) DTYMKTERTF2TK1POLB
SCHEMBL16743928 0.91 DTYMK (0.68) DTYMKTERTF2TK1POLB
SCHEMBL20090645 0.91 DTYMK (0.68) DTYMKTERTF2TK1POLB
SCHEMBL16508423 0.91 DTYMK (0.68) DTYMKTERTF2TK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3169693-B1 CHIMERIC POLYNUCLEOTIDES MODERNATX INC (US) 2022-03-09 — — EP disclosed
EP-3169335-B1 CIRCULAR POLYNUCLEOTIDES MODERNA THERAPEUTICS INC (US) 2019-08-28 — — EP disclosed
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