SCHEMBL25912829

SCHEMBL25912829

COP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H](O)C1OP(=O)(O)O[C@H]1C[C@@H](n2cc(C)c(=O)[nH]c2=O)O[C@H]1CO

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.69
▸ F2 P00734 1/20 0.57
▸ RNASEL Q05823 7/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29306731 1.00 DTYMK (0.69) DTYMKF2RNASEL
SCHEMBL25895079 0.96 DTYMK (0.70) DTYMKF2RNASEL
SCHEMBL25896356 0.96 DTYMK (0.70) DTYMKF2RNASEL
SCHEMBL27421857 0.94 DTYMK (0.68) DTYMKF2RNASEL
SCHEMBL19147022 0.94 DTYMK (0.62) DTYMKF2RNASEL
SCHEMBL27411508 0.94 DTYMK (0.67) DTYMKF2RNASEL
SCHEMBL27410764 0.93 DTYMK (0.67) DTYMKF2RNASEL
SCHEMBL21299317 0.92 DTYMK (0.63) DTYMKF2RNASEL
SCHEMBL19147041 0.91 DTYMK (0.59) DTYMKF2RNASEL
SCHEMBL25895053 0.88 DTYMK (0.67) DTYMKRNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230233475-A1 LIPID NANOPARTICLES CONTAINING POLYNUCLEOTIDES ENCODING GLUCOSE-6-PHOSPHATASE AND USES THEREOF ARES CAPITAL CORPORATION, AS AGENT 2023-07-27 — — US disclosed
US-20230130155-A1 MRNAS ENCODING METABOLIC REPROGRAMMING POLYPEPTIDES AND USES THEREOF ARES CAPITAL CORPORATION, AS AGENT 2023-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230233475-A1 LIPID NANOPARTICLES CONTAINING POLYNUCLEOTIDES ENCODING GLUCOSE-6-PHOSPHATASE AND USES THEREOF G6PC1, GNPDA1, GPI DTYMK 1763/4885F2 4882/4885RNASEL 775/4885
US-20230130155-A1 MRNAS ENCODING METABOLIC REPROGRAMMING POLYPEPTIDES AND USES THEREOF HMOX1, CD209, HMOX2 DTYMK 353/4885F2 4866/4885RNASEL 990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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