Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9957948 | 0.84 | NOTUM (0.45) | PTAFR | |
| SCHEMBL105809 | 0.82 | NPC1 (0.41) | KCNN4SMN1; SMN2 | |
| SCHEMBL1660986 | 0.80 | HTR1D (0.46) | KIF11SMN1; SMN2 | |
| SCHEMBL20410845 | 0.79 | NPC1 (0.39) | KCNN4SMN1; SMN2 | |
| SCHEMBL1338566 | 0.78 | NISCH (0.47) | SMN1; SMN2 | |
| SCHEMBL22662267 | 0.78 | ADRA2A (0.32) | KCNN4 | |
| SCHEMBL27260114 | 0.76 | NISCH (0.46) | KCNN4HDAC4HDAC2HDAC8SMN1; SMN2 | |
| SCHEMBL10520530 | 0.76 | KCNH2 (0.38) | SMN1; SMN2 | |
| Carbimide SCHEMBL29055881 | 0.76 | NPC1 (0.37) | KCNN4SMN1; SMN2 | |
| SCHEMBL23054974 | 0.75 | KCNH2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3530678-B1 | GRAFTED POLYMER WITH SOOT HANDLING PROPERTIES | AFTON CHEMICAL CORP (US) | 2021-08-18 | — | — | EP | disclosed |
| EP-3530678-A1 | GRAFTED POLYMER WITH SOOT HANDLING PROPERTIES | Afton Chemical Corporation (US) | 2019-08-28 | — | — | EP | disclosed |