Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 6/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15068728 | 1.00 | MAPT (0.39) | MAPTTP53RXFP1KDM4EALDH1A1 | |
| SCHEMBL21301259 | 0.90 | MAPT (0.38) | MAPTTP53KDM4EALDH1A1NPC1 | |
| SCHEMBL15068772 | 0.90 | GHSR (0.38) | MAPTTP53KDM4EALDH1A1NPC1 | |
| SCHEMBL15068986 | 0.90 | MAPT (0.38) | MAPTTP53KDM4EALDH1A1NPC1 | |
| SCHEMBL21301260 | 0.90 | GHSR (0.38) | MAPTTP53KDM4EALDH1A1NPC1 | |
| SCHEMBL15068964 | 0.85 | HTR7 (0.41) | MAPTTP53RXFP1KDM4EALDH1A1 | |
| SCHEMBL21301263 | 0.85 | KDM4E (0.57) | MAPTTP53KDM4EALDH1A1NPC1 | |
| SCHEMBL15068889 | 0.85 | KDM4E (0.57) | MAPTTP53KDM4EALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL15066908 | 0.84 | HTR7 (0.41) | MAPTTP53RXFP1KDM4EALDH1A1 | |
| SCHEMBL15068832 | 0.83 | ELANE (0.42) | MAPTTP53RXFP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797592-B1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS INC (US) | 2019-08-28 | — | — | EP | disclosed |