Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 2/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 9/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGAV | P06756 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PPIB | P23284 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | PPIG | Q13427 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957241 | 0.85 | NOS3 (0.55) | PPIDTAS1R3TAS1R1CTSKANPEP | |
| SCHEMBL24446769 | 0.85 | ANPEP (0.59) | TAS1R3TAS1R1CTSKANPEP | |
| SCHEMBL3955671 | 0.85 | NOS3 (0.55) | PPIDTAS1R3TAS1R1CTSKANPEP | |
| SCHEMBL3955674 | 0.85 | NOS3 (0.55) | PPIDTAS1R3TAS1R1CTSKANPEP | |
| SCHEMBL20447100 | 0.85 | ANPEP (0.59) | TAS1R3TAS1R1CTSKANPEP | |
| SCHEMBL19975277 | 0.85 | ATM (0.54) | TAS1R3TAS1R1CTSKANPEPCA12 | |
| SCHEMBL7365655 | 0.85 | ATM (0.54) | TAS1R3TAS1R1CTSKANPEPCA12 | |
| SCHEMBL6129757 | 0.85 | ATM (0.54) | TAS1R3TAS1R1CTSKANPEPCA12 | |
| SCHEMBL27723661 | 0.85 | ITGB1 (0.55) | PPIDITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL27723663 | 0.85 | ITGB1 (0.55) | PPIDITGB1ITGA5ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3530290-A1 | ALPHA AMINOACID ESTER-DRUG CONJUGATES HYDROLYSABLE BY CARBOXYLESTERASE | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-08-28 | — | — | EP | disclosed |