Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.55 |
| ▸ | NOS1 | P29475 | 2/20 | 0.55 |
| ▸ | NOS2 | P35228 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ANPEP | P15144 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957241 | 1.00 | NOS3 (0.55) | NOS3NOS1NOS2TSHRANPEP | |
| SCHEMBL3955671 | 1.00 | NOS3 (0.55) | NOS3NOS1NOS2TSHRANPEP | |
| SCHEMBL20447100 | 0.85 | ANPEP (0.59) | ANPEPMEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL21301600 | 0.85 | PPID (0.57) | ANPEPCA12CA9TAS1R3TAS1R1 | |
| SCHEMBL24446769 | 0.85 | ANPEP (0.59) | ANPEPMEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL19975277 | 0.85 | ATM (0.54) | ANPEPMEN1KMT2ACA12CA7 | |
| SCHEMBL7365655 | 0.85 | ATM (0.54) | ANPEPMEN1KMT2ACA12CA7 | |
| SCHEMBL6129757 | 0.85 | ATM (0.54) | ANPEPMEN1KMT2ACA12CA7 | |
| SCHEMBL3957176 | 0.84 | ALDH1A1 (0.49) | ANPEPCA12CA7CA9CA14 | |
| SCHEMBL3957174 | 0.84 | ALDH1A1 (0.49) | ANPEPCA12CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552208-B2 | Analogs of tetramic acid | University of Tennesseee Research Foundation (US) | 2013-10-08 | — | — | US | disclosed |
| WO-2009035553-A2 | ANALOGS OF TETRAMIC ACID | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2009-03-19 | — | — | WO | disclosed |
| US-20090069406-A1 | Analogs of tetramic acid | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-03-12 | — | — | US | disclosed |
| US-20090069406-A1 | Analogs of tetramic acid | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069406-A1 | Analogs of tetramic acid | TFRC, SLC7A1, FTH1 | NOS3 4178/4885NOS1 3068/4885NOS2 3434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.