Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | EIF2AK4 | Q9P2K8 | 3/20 | 0.32 |
| ▸ | FLT3 | P36888 | 6/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | NRAS | P01111 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21305144 | 0.86 | POLB (0.51) | POLBSCN5AMEN1KMT2AEIF2AK4 | |
| SCHEMBL21370423 | 0.80 | SCN5A (0.35) | POLBSCN5AEIF2AK4CYP1A2CYP2C9 | |
| SCHEMBL19631457 | 0.80 | CYP1A2 (0.42) | POLBSCN5ACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL18352549 | 0.76 | SCN5A (0.33) | SCN5ACYP1A2CYP2C9TGFBR1 | |
| SCHEMBL21305148 | 0.74 | APP (0.33) | PLAUELANE | |
| SCHEMBL24654977 | 0.73 | CYP1A2 (0.50) | POLBSCN5ACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL23419244 | 0.73 | SCN5A (0.38) | POLBSCN5AMEN1KMT2APLAU | |
| SCHEMBL18416824 | 0.71 | POLB (0.55) | POLBMEN1KMT2AFLT3CYP1A2 | |
| SCHEMBL30926482 | 0.71 | PIK3CA (0.43) | SCN5AEIF2AK4FLT3 | |
| SCHEMBL20208532 | 0.71 | SCN5A (0.54) | POLBSCN5AMEN1KMT2AEIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190263818-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS, INC. | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190263818-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | KLKB1, SERPINB1, SERPINE1 | POLB 4534/4885SCN5A 3000/4885MEN1 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.