Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21307971 | 0.80 | KMT2A (0.42) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AGAA | |
| SCHEMBL16024506 | 0.78 | SPHK2 (0.44) | ALDH1A1SMN1; SMN2KMT2AGAAMAPT | |
| SCHEMBL21308029 | 0.77 | MAOA (0.43) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AGAA | |
| SCHEMBL24346424 | 0.76 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AGAA | |
| SCHEMBL26167876 | 0.76 | LOX (0.43) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AGAA | |
| SCHEMBL24370868 | 0.74 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2KMT2AGAAMAPT | |
| SCHEMBL22327368 | 0.74 | GAA (0.43) | ALDH1A1KMT2AGAAMAPTPOLB | |
| SCHEMBL24199561 | 0.74 | F10 (0.40) | ALDH1A1L3MBTL1KMT2AGAAMAPT | |
| SCHEMBL23366318 | 0.74 | TP53BP1 (0.47) | ALDH1A1SMN1; SMN2KMT2AGAAMAPT | |
| SCHEMBL23106281 | 0.73 | GAA (0.39) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019164977-A1 | FLUORINATED NUCLEOTIDES AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2019-08-29 | — | — | WO | disclosed |