Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.40 |
| ▸ | GMPS | P49915 | 1/20 | 0.38 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311195 | 0.81 | EGFR (0.44) | AHCY | |
| SCHEMBL21311193 | 0.80 | DOT1L (0.38) | ADORA3ADORA2ASLC28A1GMPS | |
| SCHEMBL23025515 | 0.78 | ADORA3 (0.53) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL21311216 | 0.78 | ADORA2A (0.47) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL25521510 | 0.78 | ADORA3 (0.53) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL21311472 | 0.78 | CHKA (0.41) | PI4KAPI4K2BPI4K2API4KBSLC28A2 | |
| SCHEMBL21311476 | 0.78 | DOT1L (0.41) | ADORA3ADORA2ASLC28A1GMPS | |
| SCHEMBL20096929 | 0.78 | DOT1L (0.59) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL21311154 | 0.77 | ADORA3 (0.47) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL21311217 | 0.77 | ADORA2A (0.47) | PI4KAPI4K2BPI4K2API4KBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | POLRMT, EIF2AK2, NSUN3 | PI4KA 1441/4885PI4K2B 1610/4885PI4K2A 1284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.