SCHEMBL21311368

SCHEMBL21311368

CC(C)N1c2ccccc2Nc2ccoc21

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 1/20 0.38
CBX7 O95931 1/20 0.34
CDYL2 Q8N8U2 1/20 0.34
CDYL Q9Y232 1/20 0.34
CDY1; CDY1B Q9Y6F8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16696106 0.80 GAA (0.48) SMN1; SMN2GAA
SCHEMBL20096956 0.75 GAA (0.36) SMN1; SMN2GAA
SCHEMBL21311367 0.74 SMN1; SMN2 (0.38) SMN1; SMN2GAA
SCHEMBL13157560 0.70 SMN1; SMN2 (0.39) SMN1; SMN2GAA
SCHEMBL17297883 0.66 SMN1; SMN2 (0.39) SMN1; SMN2GAA
SCHEMBL15131073 0.66 SMN1; SMN2 (0.39) SMN1; SMN2GAA
SCHEMBL8083341 0.65 OPRM1 (0.49) SMN1; SMN2GAA
SCHEMBL24894038 0.65 SMN1; SMN2 (0.41) SMN1; SMN2GAA
SCHEMBL5000976 0.63 SMN1; SMN2 (0.46) SMN1; SMN2
SCHEMBL30396025 0.63 SMN1; SMN2 (0.46) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190262371-A1 METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190262371-A1 METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS POLRMT, EIF2AK2, NSUN3 SMN1; SMN2 959/4885GAA 435/4885CBX7 1731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.