Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 4/20 | 0.32 |
| ▸ | HTR2B | P41595 | 4/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20095511 | 0.89 | SLC6A4 (0.40) | SLC6A4HTR2AHTR1ADRD1SLC6A2 | |
| SCHEMBL20096214 | 0.89 | SLC6A4 (0.40) | SLC6A4HTR2AHTR1ADRD1SLC6A2 | |
| SCHEMBL23639043 | 0.82 | SCN9A (0.38) | SLC6A4HTR2AHTR1ASCN9AHTR2C | |
| SCHEMBL21312030 | 0.82 | SCN9A (0.38) | SLC6A4HTR2AHTR1ASCN9AHTR2C | |
| SCHEMBL15517235 | 0.82 | GRM4 (0.36) | NPY5RRIPK1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL21311815 | 0.81 | SCN9A (0.36) | SLC6A4HTR2AHTR1ADRD1SLC6A2 | |
| SCHEMBL20095514 | 0.77 | HTR2A (0.50) | SLC6A4HTR2AHTR1ASLC6A2SLC6A3 | |
| SCHEMBL20095714 | 0.77 | HTR2A (0.50) | SLC6A4HTR2AHTR1ASLC6A2SLC6A3 | |
| SCHEMBL15516297 | 0.74 | TRPM5 (0.38) | NPY5RRIPK1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL21311629 | 0.73 | HTR1A (0.38) | SLC6A4HTR2AHTR1ASCN9AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019165290-A1 | PYRIDINE-SULFONAMIDE COMPOUNDS AND THEIR USE AGAINST PAIN AND RELATED CONDITIONS | GENENTECH, INC. (US) | 2019-08-29 | — | — | WO | disclosed |