Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204150 | 0.88 | GAA (0.42) | GAAEPHX1KDM4EDPP4DPP8 | |
| SCHEMBL12910028 | 0.84 | DPP4 (0.36) | GAAEPHX1KDM4EDPP4DPP8 | |
| SCHEMBL24439496 | 0.74 | NR1H2 (0.50) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL12910026 | 0.73 | DPP4 (0.49) | EPHX1DPP4DPP8DPP7ALDH1A1 | |
| SCHEMBL13818489 | 0.73 | DPP4 (0.49) | EPHX1DPP4DPP8DPP7ALDH1A1 | |
| SCHEMBL26997891 | 0.73 | DPP8 (0.40) | GAADPP4DPP8DPP7DPP9 | |
| SCHEMBL21311706 | 0.70 | ALDH1A1 (0.30) | EPHX1ALDH1A1L3MBTL1 | |
| SCHEMBL12957888 | 0.70 | ALDH1A1 (0.54) | GAAALDH1A1EPHX2 | |
| SCHEMBL8038843 | 0.70 | ALDH1A1 (0.54) | GAAALDH1A1EPHX2 | |
| SCHEMBL10140418 | 0.70 | PDK2 (0.33) | GAAKDM4EDPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019162391-A1 | METHOD FOR PRODUCING FLUORINATED HETEROCYCLIC ALIPHATIC COMPOUNDS | Westfälische Wilhelms-Universität Münster (DE) | 2019-08-29 | — | — | WO | disclosed |