SCHEMBL21311706

SCHEMBL21311706

CC1CN(C(=O)C(F)(F)F)CC(F)C1C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12910028 0.76 DPP4 (0.36) ALDH1A1L3MBTL1EPHX1
SCHEMBL21216559 0.76 PDK2 (0.31)
SCHEMBL20204150 0.72 GAA (0.42) ALDH1A1EPHX1
SCHEMBL24782283 0.72 PDK2 (0.34)
SCHEMBL21216595 0.71 PDK2 (0.44)
SCHEMBL21311704 0.70 GAA (0.34) ALDH1A1L3MBTL1EPHX1
SCHEMBL9235459 0.69 PDK1 (0.36) EPHX1
SCHEMBL5387956 0.69 EPHX1 (0.35) EPHX1
SCHEMBL5387959 0.69 EPHX1 (0.35) EPHX1
SCHEMBL13564592 0.68 EPHX1 (0.33) ALDH1A1L3MBTL1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019162391-A1 METHOD FOR PRODUCING FLUORINATED HETEROCYCLIC ALIPHATIC COMPOUNDS Westfälische Wilhelms-Universität Münster (DE) 2019-08-29 WO disclosed