Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151304 | 1.00 | THRA (0.49) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL3919106 | 1.00 | THRA (0.49) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL1548158 | 1.00 | THRA (0.49) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL272120 | 0.94 | THRA (0.42) | THRATHRBPPARA | |
| SCHEMBL30038205 | 0.94 | THRA (0.42) | THRATHRBPPARA | |
| SCHEMBL1958087 | 0.94 | THRA (0.42) | THRATHRBPPARA | |
| SCHEMBL30823682 | 0.94 | THRA (0.42) | THRATHRBPPARA | |
| SCHEMBL10878267 | 0.93 | THRA (0.55) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL9507916 | 0.93 | THRA (0.55) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL4446002 | 0.93 | THRA (0.55) | THRATHRBPPARAPPARGLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2446005-B1 | ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY | NYCO (FR) | 2015-04-29 | — | — | EP | disclosed |
| EP-2446005-A1 | ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY | Nyco SA (FR) | 2012-05-02 | — | — | EP | disclosed |
| US-20120101015-A1 | ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY | NYCO SA (FR) | 2012-04-26 | — | — | US | disclosed |
| WO-2010149690-A1 | ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY | NYCO SA (FR) | 2010-12-29 | — | — | WO | disclosed |
| US-6093760-A | LOW VOLATILITY FLAME RETARDANT FOR A STYRENE RESIN COMPRISING HYDROGEN OR HALOGEN OR HALOGEN-FREE 1-30 CARBON ATOMS SUBSTITUTED TRIPHENYLPHOSPHATE, WHERE THE SUBSTITUENTS IN EACH PHENYL ARE DIFFERENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2000-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101015-A1 | ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY | SSB, PRNP, TARDBP | THRA 660/4885THRB 2059/4885PPARA 678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.