SCHEMBL4446002

SCHEMBL4446002

CCCCCCCCCCCCCCCCCCc1ccccc1OP(=O)(Oc1ccccc1CCCCCCCCCCCCCCCCCC)Oc1ccccc1CCCCCCCCCCCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.55
THRB P10828 1/20 0.55
PPARA Q07869 2/20 0.49
LIPG Q9Y5X9 1/20 0.49
ALOX5 P09917 1/20 0.47
PTGS2 P35354 1/20 0.47
PPARG P37231 1/20 0.47
NR1H2 P55055 1/20 0.44
NR1H3 Q13133 1/20 0.44
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
KAT8 Q9H7Z6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124086 1.00 THRA (0.55) THRATHRBPPARALIPGALOX5
SCHEMBL29522962 1.00 THRA (0.55) THRATHRBPPARALIPGALOX5
SCHEMBL9507916 1.00 THRA (0.55) THRATHRBPPARALIPGALOX5
SCHEMBL11068354 1.00 THRA (0.55) THRATHRBPPARALIPGALOX5
SCHEMBL2770599 1.00 THRA (0.55) THRATHRBPPARALIPGALOX5
SCHEMBL2821133 1.00 THRA (0.55) THRATHRBPPARALIPGALOX5
SCHEMBL10878267 1.00 THRA (0.55) THRATHRBPPARALIPGALOX5
SCHEMBL8013169 0.98 THRA (0.54) THRATHRBPPARALIPGALOX5
SCHEMBL766561 0.98 THRA (0.52) THRATHRBPPARALIPGALOX5
Phosphine SCHEMBL6813551 0.97 THRA (0.52) THRATHRBPPARALIPGALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090027586-A1 Thermoplastic Resin Composition, and Liquid Crystal Display Component Thereof or Information Recording Media Component Thereof POLYPLASTICS CO., LTD. (JP) 2009-01-29 US disclosed
EP-1992666-A1 THERMOPLASTIC RESIN COMPOSITION AND LIQUID CRYSTAL DISPLAY PART OR INFORMATION RECORDING MEDIUM PART USING THE COMPOSITION Polyplastics Co., Ltd. (JP) 2008-11-19 EP disclosed