SCHEMBL21317008

SCHEMBL21317008

O=C(NS(=O)(=O)c1ccccc1)c1cn(-c2cc(F)cc(F)c2)cn1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 8/20 0.50
▸ PTGS1 P23219 5/20 0.49
▸ ALKBH2 Q6NS38 1/20 0.48
▸ ALKBH5 Q6P6C2 1/20 0.48
▸ FTO Q9C0B1 1/20 0.48
▸ HPGD P15428 1/20 0.45
▸ P4HTM Q9NXG6 2/20 0.43
▸ KAT6A Q92794 4/20 0.42
▸ KMO O15229 1/20 0.42
▸ EGFR P00533 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ ERBB2 P04626 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21317279 0.93 PTGS2 (0.49) PTGS2PTGS1ALKBH2ALKBH5FTO
SCHEMBL21317305 0.90 NR2E1 (0.46) PTGS2PTGS1ALKBH2ALKBH5FTO
SCHEMBL21317092 0.87 PTGS2 (0.54) PTGS2PTGS1ALKBH2ALKBH5FTO
SCHEMBL21317262 0.86 PTGS2 (0.50) PTGS2PTGS1ALKBH2ALKBH5FTO
SCHEMBL21317340 0.86 PTGS2 (0.50) PTGS2PTGS1ALKBH2ALKBH5FTO
SCHEMBL21317328 0.85 PTGS2 (0.52) PTGS2PTGS1ALKBH2ALKBH5FTO
SCHEMBL21317357 0.83 PTGS2 (0.50) PTGS2PTGS1ALKBH2ALKBH5FTO
SCHEMBL21317170 0.82 PTGS2 (0.52) PTGS2PTGS1ALKBH2ALKBH5FTO
SCHEMBL21317126 0.82 HPGD (0.52) PTGS2PTGS1ALKBH2ALKBH5FTO
SCHEMBL21317193 0.82 PTGS2 (0.56) PTGS2PTGS1ALKBH2ALKBH5FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10820591-B2 Substituted sulfonyl amides for controlling animal pests BAYER AKTIENGESELLSCHAFT (DE) 2020-11-03 — — US disclosed
US-20190269134-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS BAYER AKTIENGESELLSCHAFT (DE) 2019-09-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190269134-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS MLYCD, STOM, DDT PTGS2 3333/4885PTGS1 3491/4885ALKBH2 3142/4885
US-10820591-B2 Substituted sulfonyl amides for controlling animal pests MLYCD, STOM, DDT PTGS2 3333/4885PTGS1 3491/4885ALKBH2 3142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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