SCHEMBL21317155

SCHEMBL21317155

O=C(NS(=O)(=O)c1ccccc1)c1cn(-c2ccc(Cl)c(Cl)c2)cn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMO O15229 1/20 0.55
▸ PTGS2 P35354 8/20 0.51
▸ NOTUM Q6P988 1/20 0.51
▸ PTGS1 P23219 5/20 0.47
▸ ALKBH2 Q6NS38 1/20 0.46
▸ ALKBH5 Q6P6C2 1/20 0.46
▸ FTO Q9C0B1 1/20 0.46
▸ FLT1 P17948 2/20 0.45
▸ FLT4 P35916 2/20 0.45
▸ KDR P35968 2/20 0.45
▸ CCR2 P41597 1/20 0.44
▸ RPA1 P27694 1/20 0.43
▸ GRIN2D O15399 1/20 0.43
▸ GRIN3B O60391 1/20 0.43
▸ GRIK1 P39086 1/20 0.43
▸ GRIA1 P42261 1/20 0.43
▸ GRIA2 P42262 1/20 0.43
▸ GRIA3 P42263 1/20 0.43
▸ GRIA4 P48058 1/20 0.43
▸ GRIN1 Q05586 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21317269 0.91 FLT1 (0.55) KMOPTGS2NOTUMPTGS1FLT1
SCHEMBL21317328 0.90 PTGS2 (0.52) KMOPTGS2PTGS1ALKBH2ALKBH5
SCHEMBL21317190 0.88 NOTUM (0.50) KMOPTGS2NOTUMPTGS1ALKBH2
SCHEMBL21317357 0.88 PTGS2 (0.50) KMOPTGS2PTGS1ALKBH2ALKBH5
SCHEMBL21317170 0.87 PTGS2 (0.52) KMOPTGS2PTGS1ALKBH2ALKBH5
SCHEMBL21317092 0.87 PTGS2 (0.54) KMOPTGS2PTGS1ALKBH2ALKBH5
SCHEMBL21316987 0.83 FLT1 (0.53) KMOPTGS2PTGS1ALKBH2ALKBH5
SCHEMBL21317193 0.82 PTGS2 (0.56) PTGS2PTGS1ALKBH2ALKBH5FTO
SCHEMBL21317279 0.82 PTGS2 (0.49) KMOPTGS2PTGS1ALKBH2ALKBH5
SCHEMBL21317340 0.81 PTGS2 (0.50) KMOPTGS2PTGS1ALKBH2ALKBH5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10820591-B2 Substituted sulfonyl amides for controlling animal pests BAYER AKTIENGESELLSCHAFT (DE) 2020-11-03 — — US disclosed
US-20190269134-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS BAYER AKTIENGESELLSCHAFT (DE) 2019-09-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190269134-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS MLYCD, STOM, DDT KMO 2588/4885PTGS2 3333/4885NOTUM 292/4885
US-10820591-B2 Substituted sulfonyl amides for controlling animal pests MLYCD, STOM, DDT KMO 2588/4885PTGS2 3333/4885NOTUM 292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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