Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435037 | 0.88 | KMT2A (0.44) | KMT2ALMNAMAPTTSHRALDH1A1 | |
| SCHEMBL435036 | 0.88 | KMT2A (0.44) | KMT2ALMNAMAPTTSHRALDH1A1 | |
| SCHEMBL10129753 | 0.72 | TSHR (0.47) | KMT2ALMNAMAPTTSHRALDH1A1 | |
| SCHEMBL14339400 | 0.69 | KMT2A (0.42) | KMT2ALMNAMAPTTSHRALDH1A1 | |
| SCHEMBL493850 | 0.69 | MAPT (0.45) | KMT2ALMNAMAPTTSHRALDH1A1 | |
| SCHEMBL17056905 | 0.69 | TSHR (0.53) | KMT2ALMNAMAPTTSHRALDH1A1 | |
| Phosphine SCHEMBL28141622 | 0.67 | SMN1; SMN2 (0.35) | KMT2ALMNAMAPTTSHRALDH1A1 | |
| SCHEMBL432665 | 0.66 | ALDH1A1 (0.39) | LMNATSHRALDH1A1 | |
| SCHEMBL432664 | 0.66 | ALDH1A1 (0.39) | LMNATSHRALDH1A1 | |
| SCHEMBL15101930 | 0.66 | ALDH1A1 (0.39) | LMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640236-A1 | A METHOD OF PRODUCING INGENOL-3-ANGELATE | LEO LABORATORIES LIMITED (IE) | 2020-04-22 | — | — | EP | disclosed |
| EP-2595948-B1 | A METHOD OF PRODUCING INGENOL-3-ANGELATE | LEO LABORATORIES LTD (IE) | 2019-09-04 | — | — | EP | disclosed |