Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.48 |
| ▸ | CHRNG | P07510 | 1/20 | 0.48 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.48 |
| ▸ | CHRND | Q07001 | 1/20 | 0.48 |
| ▸ | CD40 | P25942 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18515673 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BCHRNA1CHRNGCHRNB1 | |
| SCHEMBL18515734 | 0.90 | CHRNB2 (0.54) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL18495169 | 0.90 | CHRNB2 (0.54) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL18515674 | 0.88 | QRFPR (0.53) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL16867578 | 0.88 | QRFPR (0.53) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL23790017 | 0.87 | CHRNB2 (0.51) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL21320636 | 0.87 | CHRNB2 (0.51) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL18515825 | 0.87 | CHRNB2 (0.53) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL16983229 | 0.87 | AKT1 (0.47) | CHRNA1CHRNGCHRNB1CHRNDCD40 | |
| SCHEMBL18515763 | 0.87 | CHRNB2 (0.46) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130608-B1 | (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE | DAIICHI SANKYO CO LTD (JP) | 2019-09-04 | — | — | EP | disclosed |