SCHEMBL21322010

SCHEMBL21322010

CCCCCCCCc1ccc(-c2ccc(-c3ccc(OC)cc3)c(CC)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
RARB P10826 10/20 0.47
RARA P10276 2/20 0.46
RARG P13631 1/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
MTOR P42345 1/20 0.46
KMT2A Q03164 1/20 0.46
MAOB P27338 2/20 0.44
IGF1R P08069 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
PLK1 P53350 1/20 0.43
PLK3 Q9H4B4 1/20 0.43
THRA P10827 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21321754 0.99 CASP3 (0.51) CASP3SENP8SENP7SENP6RARB
SCHEMBL21321706 0.91 CASP3 (0.53) CASP3SENP8SENP7SENP6RARB
SCHEMBL19854382 0.88 MGLL (0.46) CASP3SENP8SENP7SENP6
SCHEMBL19722341 0.86 RARB (0.50) RARBRARARARGMEN1ALDH1A1
SCHEMBL12285876 0.85 RARB (0.57) CASP3SENP8SENP7SENP6RARB
SCHEMBL16807146 0.85 RARB (0.53) RARBRARARARGMEN1ALDH1A1
SCHEMBL16807155 0.85 RARB (0.53) RARBRARARARGMEN1ALDH1A1
SCHEMBL16807158 0.85 RARB (0.53) RARBRARARARGMEN1ALDH1A1
SCHEMBL16807156 0.85 RARB (0.53) RARBRARARARGMEN1ALDH1A1
SCHEMBL16807157 0.85 RARB (0.53) RARBRARARARGMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 EP disclosed