Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13469136 | 0.85 | IDH1 (0.58) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL16622505 | 0.81 | IDH1 (0.51) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL23153390 | 0.77 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL23823916 | 0.77 | IDH1 (0.55) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13531439 | 0.75 | MMP1 (0.36) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL19978233 | 0.75 | IDH1 (0.60) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13469336 | 0.74 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13469343 | 0.74 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13469357 | 0.73 | IDH1 (0.62) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13469284 | 0.73 | IDH1 (0.62) | IDH1MMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511266-B1 | LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES | UNIV CALIFORNIA (US) | 2019-09-04 | — | — | EP | disclosed |