Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13469136 | 0.93 | IDH1 (0.58) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL19978233 | 0.86 | IDH1 (0.60) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL21322283 | 0.81 | IDH1 (0.46) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL15314088 | 0.81 | IDH1 (0.54) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL11990344 | 0.80 | IDH1 (0.50) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL15314081 | 0.80 | LIPG (0.47) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL18427362 | 0.79 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13469336 | 0.79 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13469343 | 0.79 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13531440 | 0.79 | IDH1 (0.49) | IDH1MMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044090-B1 | LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES | UNIV CALIFORNIA (US) | 2015-04-08 | — | — | EP | disclosed |