SCHEMBL21322367

SCHEMBL21322367

Nc1c(O)c(-n2nc3ccccc3n2)c(O)c(-n2nc3ccccc3n2)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.43
HPGD P15428 6/20 0.43
RAB9A P51151 5/20 0.40
NPC1 O15118 3/20 0.40
LMNA P02545 3/20 0.40
ALDH1A1 P00352 7/20 0.38
MAPT P10636 6/20 0.38
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
STAT1 P42224 1/20 0.38
POLB P06746 4/20 0.36
HTT P42858 2/20 0.35
HSD17B10 Q99714 4/20 0.34
CASP1 P29466 3/20 0.34
CASP7 P55210 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
GLA P06280 2/20 0.34
CHRM2 P08172 1/20 0.34
ADRA2A P08913 1/20 0.34
ADORA3 P0DMS8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12196763 0.89 KDM4E (0.52) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL21322436 0.82 NPC1 (0.42) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL2474061 0.78 RAB9A (0.49) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL5330792 0.72 KDM4E (0.54) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL26923739 0.71 NPC1 (0.46) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL2802927 0.69 NPC1 (0.49) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL2472876 0.69 NPC1 (0.53) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL4342952 0.67 NPC1 (0.50) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL7077655 0.67 CA2 (0.44) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL26922384 0.67 NPC1 (0.50) KDM4EHPGDRAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2520972-B1 Liquid crystal display device alignment film, and method for manufacturing the same SAMSUNG DISPLAY CO LTD (KR) 2019-09-04 EP disclosed