SCHEMBL21331552

SCHEMBL21331552

[2H]C([2H])(c1ccnc(Cl)c1)C(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LOX P28300 2/20 0.53
▸ LOXL2 Q9Y4K0 2/20 0.53
▸ RECQL P46063 1/20 0.53
▸ LOXL3 P58215 1/20 0.53
▸ GRM5 P41594 1/20 0.37
▸ HDAC4 P56524 1/20 0.34
▸ HDAC1 Q13547 1/20 0.34
▸ HDAC6 Q9UBN7 1/20 0.34
▸ EPHX1 P07099 1/20 0.33
▸ TRPA1 O75762 1/20 0.33
▸ IGF1R P08069 1/20 0.33
▸ GHSR Q92847 1/20 0.33
▸ NOS3 P29474 1/20 0.32
▸ NOS1 P29475 1/20 0.32
▸ NOS2 P35228 1/20 0.32
▸ MGMT P16455 1/20 0.32
▸ SMARCA2 P51531 2/20 0.32
▸ SMARCA4 P51532 2/20 0.32
▸ AAK1 Q2M2I8 2/20 0.32
▸ FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12017629 0.81 LOX (0.57) LOXLOXL2RECQLLOXL3GRM5
SCHEMBL29874076 0.79 AR (0.37) LOXLOXL2NOS3NOS1NOS2
SCHEMBL30969437 0.74 RECQL (0.53) LOXLOXL2RECQLLOXL3GRM5
SCHEMBL805501 0.74 — —
SCHEMBL25388344 0.71 LOXL2 (0.50) LOXLOXL2RECQLLOXL3GRM5
SCHEMBL20002093 0.71 LOXL2 (0.46) LOXLOXL2RECQLLOXL3GRM5
SCHEMBL1503624 0.71 — —
Methylene Chloride SCHEMBL28291344 0.71 RECQL (0.59) LOXLOXL2RECQLLOXL3GRM5
SCHEMBL4438687 0.71 RECQL (0.59) LOXLOXL2RECQLLOXL3GRM5
SCHEMBL904475 0.70 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243229-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-07-31 — — US disclosed
US-12297212-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-05-13 — — US disclosed
EP-4489555-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2025-01-08 — — EP disclosed
EP-3539959-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-12-11 — — EP disclosed
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-11746122-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-05 — — US disclosed
US-20220135606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-05 — — US disclosed
US-11279722-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-03-22 — — US disclosed
US-11165028-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-11-02 — — US disclosed
US-11142538-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-12 — — US disclosed
US-20200199163-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-25 — — US disclosed
US-20200048290-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-02-13 — — US disclosed
EP-3539959-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-09-18 — — EP disclosed
US-20190280219-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-09-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190280219-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ESRRG, ESR2, GLRA2 LOX 2335/4885LOXL2 1476/4885RECQL 1882/4885
US-20220135606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES GLRA3, GLRA2, LIFR LOX 1038/4885LOXL2 1053/4885RECQL 836/4885
US-11279722-B2 Organic electroluminescent materials and devices GLRA3, GLRA2, LIFR LOX 977/4885LOXL2 995/4885RECQL 843/4885
US-20200048290-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ESRRG, ESR2, GLRA2 LOX 2335/4885LOXL2 1476/4885RECQL 1882/4885
US-11746122-B2 Organic electroluminescent materials and devices GLRA3, GLRA2, LIFR LOX 1038/4885LOXL2 1053/4885RECQL 836/4885
US-20250243229-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES F5, OR10J3, NPY4R LOX 160/4885LOXL2 66/4885RECQL 674/4885
US-11142538-B2 Organic electroluminescent materials and devices ESRRG, ESR2, GLRA2 LOX 2335/4885LOXL2 1476/4885RECQL 1882/4885
US-12297212-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OR10J3 LOX 326/4885LOXL2 71/4885RECQL 1215/4885
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 LOX 326/4885LOXL2 71/4885RECQL 1215/4885
US-11165028-B2 Organic electroluminescent materials and devices ESRRG, ESR2, GLRA2 LOX 2335/4885LOXL2 1476/4885RECQL 1882/4885
US-20200199163-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES GLRA3, GLRA2, LIFR LOX 977/4885LOXL2 995/4885RECQL 843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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