Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | LOX | P28300 | 1/20 | 0.59 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | NOS3 | P29474 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 1/20 | 0.53 |
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | MGMT | P16455 | 1/20 | 0.34 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805501 | 0.96 | — | — | |
| Piperazine SCHEMBL4432094 | 0.85 | RECQL (0.52) | RECQLLOXLOXL3LOXL2NOS3 | |
| SCHEMBL1503624 | 0.80 | — | — | |
| SCHEMBL4438687 | 0.79 | RECQL (0.59) | RECQLLOXLOXL3LOXL2NOS3 | |
| Hydrochloric Acid SCHEMBL7458809 | 0.78 | LOXL2 (0.63) | RECQLLOXLOXL3LOXL2NOS3 | |
| SCHEMBL14535556 | 0.77 | NOS3 (0.55) | RECQLLOXLOXL3LOXL2NOS3 | |
| SCHEMBL7455147 | 0.75 | RECQL (0.59) | RECQLLOXLOXL3LOXL2GHSR | |
| SCHEMBL22878184 | 0.75 | RECQL (0.53) | RECQLLOXLOXL3LOXL2NOS3 | |
| SCHEMBL4074777 | 0.75 | RECQL (0.53) | RECQLLOXLOXL3LOXL2MAPK14 | |
| SCHEMBL14071529 | 0.75 | RECQL (0.44) | RECQLLOXLOXL3LOXL2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-A | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | disclosed |