Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2140518 | 0.91 | MAPK1 (0.36) | ADORA2AADORA1BRD4 | |
| SCHEMBL2136669 | 0.86 | ADORA2A (0.43) | ADORA2AADORA1JAK3IGF1RFGFR1 | |
| SCHEMBL2137520 | 0.85 | ADORA2A (0.41) | ADORA2AADORA1JAK3IGF1RFGFR1 | |
| SCHEMBL2135378 | 0.85 | ABL1 (0.44) | BRD4 | |
| SCHEMBL2135041 | 0.81 | F2 (0.45) | CDK2 | |
| SCHEMBL2134202 | 0.81 | ABL1 (0.44) | — | |
| SCHEMBL10206349 | 0.80 | MAPT (0.42) | BRD4 | |
| SCHEMBL2136769 | 0.79 | CD38 (0.42) | — | |
| SCHEMBL2683381 | 0.78 | ACLY (0.37) | ADORA2AADORA1JAK3CDK2CDK9 | |
| SCHEMBL2136290 | 0.78 | SMN1; SMN2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445884-B1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2013-02-13 | — | — | EP | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| WO-2010149956-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DDT, DAO, NPM1 | ADORA2A 2623/4885ADORA1 2272/4885JAK3 3067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.