SCHEMBL21331589

SCHEMBL21331589

Clc1cccc2c1oc1cccc(-c3ccccc3-c3ccccc3Br)c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.50
ELANE P08246 1/20 0.41
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
HKDC1 Q2TB90 1/20 0.37
NPC1 O15118 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PIM1 P11309 1/20 0.36
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
PIM3 Q86V86 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
TTR P02766 2/20 0.35
NMUR2 Q9GZQ4 1/20 0.35
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
KEAP1 Q14145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27334986 0.84 AHR (0.56) AHRMAOAALDH1A1HPGDSMN1; SMN2
SCHEMBL22195636 0.84 AHR (0.59) AHRELANEMAOASMN1; SMN2TTR
SCHEMBL29450777 0.84 AHR (0.59) AHRELANEMAOASMN1; SMN2TTR
SCHEMBL25568102 0.83 AHR (0.51) AHRNPC1RAB9APIM1CSNK2A2
SCHEMBL28528988 0.81 AHR (0.53) AHRELANEMAOAHPGDSMN1; SMN2
SCHEMBL29562599 0.80 ALDH1A1 (0.48) MAOAMAOBHKDC1ALDH1A1RAB9A
SCHEMBL22763998 0.80 AHR (0.54) AHRNPC1RAB9APIM1CSNK2A2
SCHEMBL16491695 0.79 MAOA (0.44) AHRMAOAMAOBHKDC1NPC1
SCHEMBL29600921 0.79 MAOA (0.44) AHRMAOAMAOBHKDC1NPC1
SCHEMBL24031173 0.78 AHR (0.61) AHRHKDC1ALDH1A1HPGDPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243229-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-07-31 US disclosed
US-12297212-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-05-13 US disclosed
EP-4489555-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2025-01-08 EP disclosed
EP-3539959-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-12-11 EP disclosed
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-11746122-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-05 US disclosed
US-11746122-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-05 US disclosed
US-11746122-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-05 US disclosed
US-20220135606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-05 US disclosed
US-11279722-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-03-22 US disclosed
US-11165028-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-11-02 US disclosed
US-11142538-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-12 US disclosed
US-20200199163-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-25 US disclosed
US-20200048290-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-02-13 US disclosed
EP-3539959-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-09-18 EP disclosed
EP-3539959-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-09-18 EP disclosed
US-20190280219-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190280219-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ESRRG, ESR2, GLRA2 AHR 548/4885ELANE 2599/4885MAOA 2106/4885
US-20220135606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES GLRA3, GLRA2, LIFR AHR 2934/4885ELANE 2146/4885MAOA 1890/4885
US-11279722-B2 Organic electroluminescent materials and devices GLRA3, GLRA2, LIFR AHR 2930/4885ELANE 2216/4885MAOA 1894/4885
US-20200048290-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ESRRG, ESR2, GLRA2 AHR 548/4885ELANE 2599/4885MAOA 2106/4885
US-11746122-B2 Organic electroluminescent materials and devices GLRA3, GLRA2, LIFR AHR 2934/4885ELANE 2146/4885MAOA 1890/4885
US-20250243229-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES F5, OR10J3, NPY4R AHR 1583/4885ELANE 1019/4885MAOA 543/4885
US-11142538-B2 Organic electroluminescent materials and devices ESRRG, ESR2, GLRA2 AHR 548/4885ELANE 2599/4885MAOA 2106/4885
US-12297212-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OR10J3 AHR 1670/4885ELANE 2230/4885MAOA 298/4885
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 AHR 1670/4885ELANE 2230/4885MAOA 298/4885
US-11165028-B2 Organic electroluminescent materials and devices ESRRG, ESR2, GLRA2 AHR 548/4885ELANE 2599/4885MAOA 2106/4885
US-20200199163-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES GLRA3, GLRA2, LIFR AHR 2930/4885ELANE 2216/4885MAOA 1894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.