Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29822698 | 0.81 | ALDH1A1 (0.41) | MAPTTDP1ALDH1A1NSD2EGFR | |
| SCHEMBL229536 | 0.81 | ALDH1A1 (0.41) | MAPTTDP1ALDH1A1NSD2EGFR | |
| SCHEMBL29444117 | 0.81 | ALDH1A1 (0.41) | MAPTTDP1ALDH1A1NSD2EGFR | |
| Bromide SCHEMBL1033291 | 0.79 | ALDH1A1 (0.39) | MAPTTDP1ALDH1A1NSD2EGFR | |
| SCHEMBL21333878 | 0.78 | ALDH1A1 (0.40) | MAPTTDP1ALDH1A1NSD2EGFR | |
| SCHEMBL3665710 | 0.78 | TDP1 (0.39) | MAPTTDP1ALDH1A1NSD2EGFR | |
| SCHEMBL2919461 | 0.77 | MAPT (0.52) | MAPTTDP1ALDH1A1NSD2EGFR | |
| SCHEMBL1033292 | 0.76 | ALDH1A1 (0.37) | MAPTTDP1ALDH1A1NSD2EGFR | |
| SCHEMBL29513054 | 0.75 | MAPT (0.50) | MAPTTDP1ALDH1A1NSD2EGFR | |
| SCHEMBL17606910 | 0.75 | MAPT (0.50) | MAPTTDP1ALDH1A1NSD2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3766891-B1 | TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS | DONGGUAN STEPHEN CATALYST CO LTD (CN) | 2023-11-01 | — | — | EP | claimed |
| CN-110240616-B | Tribiaryl monophosphine ligands, methods for their preparation and use in catalytic coupling reactions | 东莞市均成高新材料有限公司 | 2021-03-23 | — | — | CN | claimed |
| WO-2019170163-A1 | TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS | 东莞市均成高新材料有限公司 | 2019-09-12 | — | — | WO | claimed |
| CN-110240616-B | Tribiaryl monophosphine ligands, methods for their preparation and use in catalytic coupling reactions | 东莞市均成高新材料有限公司 | 2021-03-23 | — | — | CN | disclosed |
| WO-2019170163-A1 | TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS | 东莞市均成高新材料有限公司 | 2019-09-12 | — | — | WO | disclosed |