SCHEMBL2919461

SCHEMBL2919461

CN(C)c1ccccc1-c1ccccc1N(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.52
ALDH1A1 P00352 4/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
NSD2 O96028 1/20 0.52
EGFR P00533 1/20 0.52
LMNA P02545 1/20 0.52
MAPK1 P28482 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
GAA P10253 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
KDM4E B2RXH2 1/20 0.48
CHEK1 O14757 1/20 0.46
NEK2 P51955 1/20 0.46
LIMK1 P53667 1/20 0.46
DYRK1A Q13627 1/20 0.46
CLK4 Q9HAZ1 1/20 0.46
KCNN4 O15554 1/20 0.42
HTR6 P50406 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3965515 0.87 ALDH1A1 (0.44) MAPTALDH1A1L3MBTL1NSD2EGFR
SCHEMBL19698852 0.86 MAPT (0.47) MAPTALDH1A1L3MBTL1NSD2EGFR
SCHEMBL2491630 0.85 MAPT (0.42) MAPTALDH1A1L3MBTL1NSD2EGFR
SCHEMBL3792075 0.85 ALDH1A1 (0.59) MAPTALDH1A1L3MBTL1NSD2EGFR
SCHEMBL413186 0.85 ALDH1A1 (0.44) MAPTALDH1A1L3MBTL1NSD2EGFR
SCHEMBL1931334 0.85 MAPT (0.42) MAPTALDH1A1L3MBTL1NSD2EGFR
SCHEMBL366889 0.85 MAPT (0.42) MAPTALDH1A1L3MBTL1NSD2EGFR
SCHEMBL9277375 0.85 EP300 (0.45) MAPTALDH1A1L3MBTL1NSD2EGFR
SCHEMBL1254512 0.84 ALDH1A1 (0.45) MAPTALDH1A1L3MBTL1NSD2EGFR
SCHEMBL9322493 0.84 MAPT (0.45) MAPTALDH1A1L3MBTL1NSD2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2221289-B1 METHOD OF PRODUCING ALCOHOL MITSUBISHI CHEM CORP (JP) 2016-10-26 EP disclosed
US-8318990-B2 Process of producing alcohol MITSUBISHI CHEMICAL CORPORATION (JP) 2012-11-27 US disclosed
US-20100298613-A1 PROCESS OF PRODUCING ALCOHOL MITSUBISHI CHEMICAL CORPORATION (JP) 2010-11-25 US disclosed
EP-2221289-A1 METHOD OF PRODUCING ALCOHOL Mitsubishi Chemical Corporation (JP) 2010-08-25 EP disclosed
US-4645837-A GROUP 8 METAL CARBONYL COMPLEX SRI INTERNATIONAL (US) 1987-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298613-A1 PROCESS OF PRODUCING ALCOHOL ADH1C, ADH1A, ADH5 MAPT 222/4885ALDH1A1 79/4885L3MBTL1 3461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.