Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28415061 | 0.87 | L3MBTL1 (0.44) | SLC22A12L3MBTL1GLATBXAS1PTGDR2 | |
| SCHEMBL21331860 | 0.86 | CYP2C9 (0.54) | SLC22A12L3MBTL1TBXAS1CYP2C9HIF1A | |
| SCHEMBL21350750 | 0.85 | PTGDR2 (0.45) | SLC22A12L3MBTL1GLATBXAS1PTGDR2 | |
| SCHEMBL28411914 | 0.84 | KMT2A (0.39) | SLC22A12CYP2C9HIF1AALDH1A1POLB | |
| SCHEMBL21350302 | 0.83 | TBXAS1 (0.41) | SLC22A12L3MBTL1TBXAS1PTGDR2KDM4E | |
| SCHEMBL28411844 | 0.83 | PTGDR2 (0.41) | SLC22A12L3MBTL1TBXAS1PTGDR2KDM4E | |
| SCHEMBL21331807 | 0.83 | SLC22A12 (0.43) | SLC22A12L3MBTL1TBXAS1PTGDR2HIF1A | |
| SCHEMBL21334005 | 0.83 | SLC22A12 (0.44) | SLC22A12CYP2C9HIF1AKDM4EALDH1A1 | |
| SCHEMBL21350515 | 0.81 | SLC22A12 (0.59) | SLC22A12 | |
| SCHEMBL21331848 | 0.80 | SLC22A12 (0.48) | SLC22A12TBXAS1PTGDR2CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | claimed |
| CN-108440397-B | 3- (naphthalene-1-methyl substituted) pyridine derivative and synthesis method and application thereof | 南方医科大学 | 2020-06-05 | — | — | CN | disclosed |
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | disclosed |