Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 8/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 8/20 | 0.43 |
| ▸ | KIT | P10721 | 4/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21339753 | 0.84 | KIT (0.46) | KIT | |
| SCHEMBL21339637 | 0.83 | KIT (0.42) | LIMK1LIMK2KIT | |
| SCHEMBL27929255 | 0.78 | TRPV1 (0.41) | LIMK1LIMK2TRPV1 | |
| SCHEMBL22899639 | 0.73 | DRD4 (0.34) | KIT | |
| SCHEMBL2636728 | 0.71 | NAMPT (0.46) | — | |
| SCHEMBL21994832 | 0.71 | CNR1 (0.43) | — | |
| SCHEMBL23235670 | 0.71 | ALDH1A1 (0.43) | TRPV1 | |
| SCHEMBL21332342 | 0.70 | KIT (0.46) | KIT | |
| SCHEMBL16793728 | 0.70 | CCNT1 (0.39) | — | |
| SCHEMBL2266251 | 0.69 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3762379-A1 | IDENTIFICATION AND USE OF ERK5 INHIBITORS | Bayer Aktiengesellschaft (DE) | 2021-01-13 | — | — | EP | disclosed |
| WO-2019170543-A1 | IDENTIFICATION AND USE OF ERK5 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-12 | — | — | WO | disclosed |