Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 7/20 | 0.42 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 10/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 10/20 | 0.42 |
| ▸ | QDPR | P09417 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21332342 | 0.87 | KIT (0.46) | KITMAPK7 | |
| SCHEMBL21332385 | 0.83 | LIMK1 (0.43) | KITLIMK1LIMK2 | |
| SCHEMBL22324984 | 0.73 | QDPR (0.47) | QDPRTDP1 | |
| SCHEMBL21339753 | 0.73 | KIT (0.46) | KIT | |
| SCHEMBL21339752 | 0.72 | MAPK7 (0.66) | MAPK7 | |
| SCHEMBL21332199 | 0.70 | KIT (0.47) | KITMAPK7LIMK1LIMK2 | |
| SCHEMBL21332105 | 0.70 | MAPK7 (0.42) | KITMAPK7LIMK1LIMK2QDPR | |
| SCHEMBL14562979 | 0.69 | QDPR (0.53) | QDPRTDP1 | |
| SCHEMBL28868855 | 0.69 | ACHE (0.41) | MAPK7QDPR | |
| SCHEMBL27828522 | 0.68 | LIMK1 (0.39) | KITLIMK1LIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170543-A1 | IDENTIFICATION AND USE OF ERK5 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-12 | — | — | WO | disclosed |