Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 14/20 | 0.70 |
| ▸ | FPR2 | P25090 | 12/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21332085 | 1.00 | FPR1 (0.70) | FPR1FPR2MAPTMEN1ALDH1A1 | |
| SCHEMBL21332017 | 0.95 | FPR2 (0.65) | FPR1FPR2MAPTMEN1ALDH1A1 | |
| SCHEMBL21342554 | 0.95 | FPR2 (0.65) | FPR1FPR2MAPTMEN1ALDH1A1 | |
| SCHEMBL21332135 | 0.95 | FPR2 (0.65) | FPR1FPR2MAPTMEN1ALDH1A1 | |
| SCHEMBL21332232 | 0.95 | FPR1 (0.67) | FPR1FPR2MAPTMEN1ALDH1A1 | |
| SCHEMBL21341984 | 0.93 | FPR1 (0.72) | FPR1FPR2MAPTMEN1ALDH1A1 | |
| SCHEMBL21332100 | 0.93 | FPR1 (0.72) | FPR1FPR2MAPTMEN1ALDH1A1 | |
| SCHEMBL21332102 | 0.93 | FPR1 (0.72) | FPR1FPR2MAPTMEN1ALDH1A1 | |
| SCHEMBL21331985 | 0.91 | FPR1 (0.69) | FPR1FPR2MAPTMEN1ALDH1A1 | |
| SCHEMBL21341985 | 0.91 | FPR1 (0.69) | FPR1FPR2MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |