Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18497479 | 0.89 | DPP4 (0.34) | DPP4DPP8DPP9BCHECHRM4 | |
| SCHEMBL8683160 | 0.79 | SMN1; SMN2 (0.35) | DPP4DPP8DPP9BCHECHRM4 | |
| SCHEMBL19434650 | 0.77 | CA12 (0.32) | RAB9A | |
| SCHEMBL28209789 | 0.76 | DPP4 (0.39) | DPP4RAB9AACE | |
| SCHEMBL2428695 | 0.76 | DPP4 (0.39) | DPP4RAB9AACE | |
| SCHEMBL8682408 | 0.75 | ALDH1A1 (0.38) | DPP4DPP8DPP9BCHE | |
| SCHEMBL16554809 | 0.72 | CA12 (0.33) | — | |
| SCHEMBL23795169 | 0.71 | ALDH1A1 (0.38) | DPP4DPP8DPP9RAB9ADPP7 | |
| SCHEMBL29126180 | 0.71 | HSD17B10 (0.39) | DPP4DPP8DPP9RAB9ADPP7 | |
| SCHEMBL24663899 | 0.71 | DPP4 (0.32) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019173505-A1 | METHODS OF TREATING DISORDERS RELATED TO GLYCEMIC CONTROL | ZAFGEN, INC. (US) | 2019-09-12 | — | — | WO | disclosed |