Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681185 | 0.83 | BCHE (0.49) | SMN1; SMN2BCHECHRNB2CHRNA5CHRNA7 | |
| SCHEMBL8686148 | 0.81 | BCHE (0.43) | SMN1; SMN2DPP4DPP8DPP9BCHE | |
| SCHEMBL21333720 | 0.79 | DPP4 (0.40) | DPP4DPP8DPP9BCHECHRM4 | |
| SCHEMBL3905171 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL688825 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL688697 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL8682408 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2DPP4DPP8DPP9BCHE | |
| Hydrochloric Acid SCHEMBL21801417 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8704065 | 0.77 | SMN1; SMN2 (0.37) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL8682105 | 0.74 | CHRM1 (0.44) | SMN1; SMN2BCHECHRM1CHRM3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843983-A | Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| US-5556864-A | TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |