Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21345593 | 0.88 | MEN1 (0.36) | MEN1USP2POLBKMT2AP2RY2 | |
| SCHEMBL21055674 | 0.88 | MEN1 (0.36) | MEN1USP2POLBKMT2AP2RY2 | |
| SCHEMBL21333757 | 0.80 | — | — | |
| SCHEMBL31388523 | 0.78 | NT5E (0.36) | P2RY2P2RY6LMNATHRB | |
| SCHEMBL6760519 | 0.76 | POLB (0.54) | MEN1USP2POLBKMT2AP2RY6 | |
| SCHEMBL6760520 | 0.76 | POLB (0.54) | MEN1USP2POLBKMT2AP2RY6 | |
| SCHEMBL10459827 | 0.76 | POLB (0.54) | MEN1USP2POLBKMT2AP2RY6 | |
| SCHEMBL18512719 | 0.75 | LMNA (0.42) | LMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL21345149 | 0.74 | ALDH1A1 (0.38) | P2RY2P2RY4P2RY6LMNA | |
| SCHEMBL18503481 | 0.73 | LMNA (0.32) | LMNATHRBSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3762372-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | Emory University (US) | 2021-01-13 | — | — | EP | disclosed |
| WO-2019173602-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2019-09-12 | — | — | WO | disclosed |