Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.46 |
| ▸ | LATS1 | O95835 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | BRS3 | P32247 | 2/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28408726 | 0.88 | SLC22A12 (0.46) | SLC22A12LATS1KDM4CBRS3FTO | |
| SCHEMBL21350533 | 0.86 | LATS1 (0.43) | SLC22A12LATS1MAPK8MAPK9MAPK10 | |
| SCHEMBL21331805 | 0.84 | SLC22A12 (0.44) | SLC22A12LATS1KDM4C | |
| SCHEMBL28412038 | 0.84 | SLC22A12 (0.66) | SLC22A12 | |
| SCHEMBL21331842 | 0.80 | SLC22A12 (0.39) | SLC22A12KDM4CNUDT1PIM1FLT3 | |
| SCHEMBL21333891 | 0.78 | SLC22A12 (0.72) | SLC22A12 | |
| SCHEMBL21331818 | 0.78 | SLC22A12 (0.46) | SLC22A12 | |
| SCHEMBL21350630 | 0.75 | LATS1 (0.45) | SLC22A12LATS1KDM4CMAPK8MAPK9 | |
| SCHEMBL21350532 | 0.74 | ELANE (0.41) | SLC22A12MAPK8MAPK9MAPK10ROCK2 | |
| SCHEMBL21350908 | 0.73 | CCNC (0.44) | SLC22A12FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440397-B | 3- (naphthalene-1-methyl substituted) pyridine derivative and synthesis method and application thereof | 南方医科大学 | 2020-06-05 | — | — | CN | disclosed |
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | disclosed |